
You should
keep them in spacious carriers inside your car with water available at
all times. Icecubes in a dish can provide a constant supply of cold
water that doesn't spill easily. Keep the carrier on the seat or
floor near you, so you can be aware of their condition, and make sure
the sun and air conditioner is not a problem for them. Feed them their
regular food at regular meal times. Provide a cat box in the carrier,
using shredded paper if sand spillage is a problem. Do not let them
outside at rest stops or motels, for the may run away in the confusion.
You can let them out in a securely closed motel room. Consider having
an airline fly them out, for this minimizes stress by being faster. Pet
airline travel is safer and less expensive than most people think.
Tranquilizers are not a good idea for trips longer than eight hours.