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Motor Neuron Disease

image I have a 15 year old neutered male that has been in good health up until two weeks ago. He has lost control of his motor function. His Dr. has run blood tests, thyroid and potassium tests as well as x-rays to no avail. He was put on prednisone 5mg/2x for the first 3 days and then weaned to 5mg 1x. His symptoms returned and appeared to have worsened. He is back on the 5mg 2x. He had a similar spell 7 years ago that his first doctor attributed to the recent immunizations he received. Since that time, I no longer have him immunized. His current Dr. states the next step is a neurological work up that includes an MRI. He did not feel optimistic that this would identify this problem. Any suggestions I can pass on to him? Also, what are the effects of long term usage of prednisone? Thank you so much.
image His problems sound severe, and definitely deserve a thorough investigation. A precise physical and complete neurological examination by your veterinarian will be able to pin point the areas of his nervous system originating the problem. The cause of the problem is more difficult to determine than the location. For each possible location, there is a set of possible causes. For instance, a peripheral motor neuron disease may be due to a severe allergic reaction, whereas a central nervous system problem can be caused by a tumor or stroke. Of course, many other diseases are possible. An MRI should only be considered once the general location of the lesion is known, it is in the central nervous system, and you need to determine the precise location. MRI technology is also beneficial in identifying the cause of the lesion, i.e. differentiating between a stroke and a tumor.

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