
You may
have a physical problem with the male or female, or a problem with the
cycle timing. You may consider having the male's semen evaluated
for numbers and vitality. Male semen inadequacy is very common. If the
female is not behaviorally clear when she is in heat, you may be
missing the prime period of her cycles. Different than dogs, queens are
induced ovulators, which makes it less crucial to breed at a precise
time. I recommend thorough general physical examinations and breeding
examinations by your veterinarian. Your veterinarian my wish to keep
both for more than a day to collect semen samples and vaginal smears.
Although cats can be hormonally manipulated to synchronize breeding,
and queens can be artificially inseminated, you should look for the
obvious problems first.